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Lexapro is the trademark name for the generic drug escitalopram, which is a type of antidepressant medication. It belongs to a group of antidepressants called selective serotonin reuptake inhibitors that were first introduced in the 1980. These medications are generally effective and have fewer side effects than some other antidepressants such as monoamine oxidase inhibitors.

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Description

Use of Lexapro

Lexapro was initially used only to treat depression. However, research began to show that it was also effective for other mood disorders as well as anxiety disorders. While it is currently only approved by the Food and Drug Administration (FDA) for the treatment of depression and generalized anxiety disorder (GAD), it is prescribed for many other conditions.

Doctors sometimes prescribe Lexapro off-label for illnesses such as bipolar disorder, obsessive-compulsive disorder (OCD), panic disorder (with or without agoraphobia), post-traumatic stress disorder (PTSD), social anxiety disorder (SAD), migraines, and chronic pain.

How It Works

It is not known exactly how Lexapro works to reduce symptoms of depression and anxiety. However, we know that this medication has an effect on serotonin, which is a brain neurotransmitter involved in mood, sleep, and other bodily functions. It is thought that by taking Lexapro, serotonin levels in your brain become more balanced, which helps to reduce anxiety and enhance your mood.

Efficacy

Lexapro is an allosteric serotonin reuptake inhibitor, which differentiates it from other SSRIs. There is some evidence that it is more effective than a range of other antidepressants. It is often the first choice because of its efficacy and tolerability.

How to Take It

Dosage

You may take Lexapro as tablets or an oral solution once daily, in the morning or evening, with or without food. The usual recommended daily dosage of Lexapro is 10 mg, but your doctor may begin at a lower dose. The dosage can be increased slowly to 20 mg or higher if needed. Doses higher than 20 mg are not approved by the FDA. Staying within the recommended dose helps to reduce the risk of side effects or adverse reactions.3

If you are experiencing the first episode of depression or anxiety, you may take Lexapro for a defined period such as between six months and one year. However, for individuals experiencing a chronic mental health condition, it may be necessary to take Lexapro for an extended period over many years.

Missed Doses

Missed doses should be taken as soon as you remember unless it is very close to your next dose, in which case you should take your regular dose instead. Never take two or more doses of Lexapro together at the same time. Taking your medication as prescribed will ensure that you experience its full effectiveness.

How Long it Takes to Work

It can take anywhere from one to four weeks to feel better once you start taking Lexapro, and you may not experience the full benefits of the medication until you’ve been following a recommended treatment plan for several months.

Side Effects

The most common side effects of taking Lexapro are listed below. As your body adjusts to taking the medication, you should gradually notice that the side effects go away.5 If you notice that side effects are getting worse or are interfering with your quality of life, talk to your doctor about your concerns. Side effects can be minimized by carefully following the dosage directions given by your doctor and reporting any negative effects.

  • Sleep disturbances
  • Nausea
  • Headaches
  • Blurred vision
  • Dry mouth
  • Diarrhea
  • Stomach pain
  • Constipation

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