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Ultram and Ultram ER are the brand names of the drug tramadol. They are available in the form of immediate and extended release tablets. Tramadol is also combined with acetaminophen in the drug Ultracet. Tramadol acts on two compounds associated with the sensation of pain: serotonin and norepinephrine.

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What are the side effects of tramadol?

Tramadol is a prescription pain medication that can help with moderate to severe pain. It has a number of side effects, however, including dizziness, nausea, sweating, and heartburn. Less common side effects include confusion and hives. Doctors only prescribe tramadol to people over 12 years old. Adolescents with certain risk factors should speak with their doctors about the risks of taking tramadol. Some people take tramadol for premature ejaculation and restless legs syndrome, but the Food and Drug Administration (FDA) have not approved these uses of it. As an opioid drug, tramadol acts on the brain to relieve pain. However, tramadol is not as effective as morphine, which is another opioid. Because of its opioid activity, people can become dependent on tramadol. In this article, we discuss the side effects of tramadol. We will also take a look at tramadol dependence.

What is tramadol?

Ultram and Ultram ER are the brand names of the drug tramadol. They are available in the form of immediate and extended release tablets. Tramadol is also combined with acetaminophen in the drug Ultracet. Tramadol acts on two compounds associated with the sensation of pain: serotonin and norepinephrine. Tramadol helps relieve pain by decreasing the amount of these two compounds in brain cells. Liver enzymes break down tramadol into another compound called O-desmethyltramadol, which binds to the opioid receptor. This is the same receptor that morphine binds to, but tramadol is not as strong as morphine; its efficacy is “about one-tenth that of morphine.” The FDA classify tramadol as a schedule IV drug because of its potential for misuse and addiction. It belongs to the same schedule as Xanax, Soma, and Valium. Doctors should choose the lowest effective dosage for the shortest period and educate people on the possible risks of taking tramadol.

Side effects

Tramadol can cause side effects in some people. They occur more often when people first start taking tramadol and can wear off over time.

  • Common side effects
  • tramadol side effects
  • Side effects of tramadol include dizziness, nausea, and headaches.
  • The most common side effects of tramadol affect the abdominal tract and the brain.

The following list provides common side effects that occur in 5% or more of people who take tramadol:

  • dizziness and vertigo
  • nausea
  • constipation
  • headache
  • drowsiness
  • vomiting
  • itchiness
  • stimulation of the central nervous system
  • weakness
  • sweating
  • heartburn
  • dry mouth
  • diarrhea

Less common side effects

People may experience other side effects that occur with an incidence of less than 5%, such as:

  • whole body discomfort
  • allergic reactions
  • suicidal tendencies
  • weight loss
  • rapid heartbeat
  • drop in blood pressure upon standing up
  • confusion
  • disturbance in coordination
  • constriction of the pupil
  • fainting
  • rash
  • hives
  • visual disturbance
  • menopausal symptoms
  • retention of urine
  • difficulty breathing
  • frequent urination
  • serotonin syndrome

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